4-(Trifluoromethyl)phenylhydrazine → 4-[[2-[[4-(Trifluoromethyl)phenyl]hydrazono]propyl]oxy]benzonitrile

HRID 2233764

Reaction equation

HRID 2233764 reaction equation
O=[C:2]([CH3:13])[CH2:3][O:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][CH:6]=1.[F:14][C:15]([F:25])([F:24])[C:16]1[CH:21]=[CH:20][C:19]([NH:22][NH2:23])=[CH:18][CH:17]=1>>[F:14][C:15]([F:24])([F:25])[C:16]1[CH:17]=[CH:18][C:19]([NH:22][N:23]=[C:2]([CH3:13])[CH2:3][O:4][C:5]2[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][CH:6]=2)=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 1362004-(Trifluoromethyl)phenylhydrazineHCID 3096034-(2-Oxopropoxy)benzonitrile

Product 1

HCID 860348074-[[2-[[4-(Trifluoromethyl)phenyl]hydrazono]propyl]oxy]benzonitrile

Procedure

The sub-title compound was prepared by the method of example 20 step (ii), using the product from step (i) (3.8 g) and 4-(trifluoromethyl)phenylhydrazine (3.7 g). Yield 2.8 g.

Sources & evidence

ORD record
ord-3595a7e88c21468b971e160addb289f5
Source dataset
uspto-grants-2010_05
Patent number
US07709521B2

Linked notes

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