Hydrochloric Acid → 7-Chlorobenzo[d]thiazol-2(3H)-one

HRID 223397

Reaction equation

[Cl:1][C:2]1[C:10]2[S:9][C:8]([O:11]CC)=[N:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.Cl>>[Cl:1][C:2]1[C:10]2[S:9][C:8](=[O:11])[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 205222777-Chloro-2-ethoxybenzothiazole

Product 1

HCID 132273397-Chlorobenzo[d]thiazol-2(3H)-oneYield 38%

Procedure

Prepared analogous to Example 5 from 7-chloro-2-ethoxy-benzothiazole and concentrated hydrochloric acid with a yield of 38% of theory. M.p.: 202°-203° C. (after recrystallization from methanol and from diisopropyl ether).

Workup

customM.p.: 202°-203° C. (after recrystallization from methanol and from diisopropyl ether)

Sources & evidence

ORD record: ord-8e338d60b40c46aa99a4ed367630d97c
Source dataset: uspto-grants-1982_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04353919

Linked notes

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