Methyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethyl phosphono)acetate → Methyl(2Z)-2-{[(benzyloxy)carbonyl]amino}-3-(6-trifluoromethylpyridin-3-yl)acrylate
Reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[N:8]=[CH:7][C:6]([CH:9]=O)=[CH:5][CH:4]=1.[CH2:13]([O:20][C:21]([NH:23][CH:24](P(OC)(OC)=O)[C:25]([O:27][CH3:28])=[O:26])=[O:22])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C1COCC1>[CH2:13]([O:20][C:21]([NH:23]/[C:24](=[CH:9]\[C:6]1[CH:7]=[N:8][C:3]([C:2]([F:12])([F:11])[F:1])=[CH:4][CH:5]=1)/[C:25]([O:27][CH3:28])=[O:26])=[O:22])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- -70 °C