Hydrazine hydrate (1:1) → 3-(2-Methoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[c]pyridazine

HRID 2243929Notes

Reaction equation

HRID 2243929 reaction equation
[C:1]1(=O)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]1=O.COP([CH2:16][C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[O:25][CH3:26])=O)(=O)OC.O.[NH2:28][NH2:29]>>[CH3:26][O:25][C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=1[C:17]1[N:29]=[N:28][C:2]2[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:1]=2[CH:16]=1

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 763651,2-CycloheptanedioneHCID 86252899HCID 86252899, compound

Product 1

HCID 160637033-(2-Methoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[c]pyridazine

Procedure

light yellow gum. MS (ESI): 255.2 (MH+). Prepared from cycloheptane-1,2-dione, [2-(2-Methoxy-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-18a4929c76cc4794864f701ed60b9f11
Source dataset
uspto-grants-2010_03
Patent number
US07678795B2

Reaction notes

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