Hydrazine hydrate (1:1) → HCID 67363679, compound
Reaction equation
[CH3:1][C@@:2]12[C:8]([CH3:10])([CH3:9])[C@@H:5]([CH2:6][CH2:7]1)[C:4](=O)[C:3]2=O.COP([CH2:19][C:20]([C:22]1[CH:27]=[CH:26][C:25]([F:28])=[CH:24][C:23]=1[CH3:29])=O)(=O)OC.O.[NH2:31][NH2:32]>>[F:28][C:25]1[CH:26]=[CH:27][C:22]([C:20]2[N:31]=[N:32][C:3]3[C@:2]4([CH3:1])[C:8]([CH3:10])([CH3:9])[C@H:5]([C:4]=3[CH:19]=2)[CH2:6][CH2:7]4)=[C:23]([CH3:29])[CH:24]=1Participants
4
Procedure
yellow solid. MS (ESI): 297.3 (MH+). Prepared from (1S,4R)-1,7,7-trimethyl-bicyclo [2.2.1]heptane-2,3-dione, [2-(4-Fluoro-2-methyl-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.
Sources & evidence
- ORD record
- ord-3d1779c68e6f4db3af8c46a807e5d9f9
- Source dataset
- uspto-grants-2010_03