Hydrogen Peroxide → HCID 178433055, compound

HRID 224776Notes

Reaction equation

HRID 224776 reaction equation
OO.[CH3:3][S:4][CH2:5][C:6]1[N:11]=[C:10]([OH:12])[C:9]([CH3:13])=[C:8]([CH3:14])[N:7]=1.CC[O:17]CC>C(O)(=O)C>[CH3:3][S:4]([CH2:5][C:6]1[N:11]=[C:10]([OH:12])[C:9]([CH3:13])=[C:8]([CH3:14])[N:7]=1)=[O:17]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 3283Diethyl EtherHCID 178503663HCID 178503663, compound

Product 1

HCID 178433055HCID 178433055, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

6.8 g (0.1 mol) of 50% strength hydrogen peroxide were added to a mixture of 18.4 g (0.1 mol) of 2-methylthiomethyl-4-hydroxy-5,6-dimethylpyrimidine in 100 ml of glacial acetic acid at 10° C. The mixture was subsequently stirred for 3 hours, without cooling, about 300 ml of ether were added and the product which had precipitated was filtered off. 17 g (85% of theory) of 2-methysulphinylmethyl-4-hydroxy-5,6-dimethylpyrimidine were thus obtained in the form of a grey powder with a melting point of 112° C. ##STR7##

Workup

  1. temperaturewithout cooling
  2. customthe product which had precipitated
  3. filtrationwas filtered off

Sources & evidence

ORD record
ord-9e5355ceecc2404b9ab66c2cbd785817
Source dataset
uspto-grants-1980_11
Patent number
US04234587

Reaction notes

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