Hydrochloric Acid → 1-(4-Oxazol-2-yl-phenyl)-piperazine hydrochloride
Reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[O:21][CH:22]=[CH:23][N:24]=3)=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:25]>O1CCOCC1>[ClH:25].[O:21]1[CH:22]=[CH:23][N:24]=[C:20]1[C:17]1[CH:16]=[CH:15][C:14]([N:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[CH:19][CH:18]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared in analogy to example 4.4 (b) from 4-(4-Oxazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and hydrochloric acid in dioxane. MS (m/e): 230.1 (MH+, 100%)
Sources & evidence
- ORD record
- ord-8e2f4c98115746519da7b20f6f16aaec
- Source dataset
- uspto-grants-2008_01
- Patent number
- US07319099B2
Reaction notes
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