Methylamine → N,1-dimethyl-3-nitro-4-pyrazolecarboxamide
Reaction equation
[CH3:1][NH2:2].[CH3:3][N:4]1[CH:8]=[C:7]([C:9](Cl)=[O:10])[C:6]([N+:12]([O-:14])=[O:13])=[N:5]1>O>[CH3:1][NH:2][C:9]([C:7]1[C:6]([N+:12]([O-:14])=[O:13])=[N:5][N:4]([CH3:3])[CH:8]=1)=[O:10]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Fifty ml. of water was cooled in an ice bath and saturated with monomethylamine. To the solution was added 2 gm. of 1-methyl-3-nitro-4-pyrazolecarbonyl chloride in portions, and the mixture was heated until the solid dissolved. Upon cooling a solid precipitated which was recrystallized from water and identified as 1.3 gm. of N,1-dimethyl-3-nitro-4-pyrazolecarboxamide, m.p. 163°-165° C.
Workup
- additionTo the solution was added 2 gm
- dissolutiondissolved
- temperatureUpon cooling a solid
- customprecipitated which
- customwas recrystallized from water
Sources & evidence
- ORD record
- ord-d21fc62033dd44fcaa82802a1d93a767
- Source dataset
- uspto-grants-1980_11
- Patent number
- US04235995
Reaction notes
Loading…