Lithium Hydroxide → (R)-1-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-2-[4-(4-carboxymethyl-piperazin-1-yl)-piperidin-1-yl]-2-oxo-ethyl 4-(7-methoxy-2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carboxylate

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[NH:12][C:11](=[O:13])[N:10]([CH:14]3[CH2:19][CH2:18][N:17]([C:20]([O:22][C@H:23]([CH2:44][C:45]4[CH:50]=[C:49]([C:51]([F:54])([F:53])[F:52])[C:48]([NH2:55])=[C:47]([Cl:56])[CH:46]=4)[C:24]([N:26]4[CH2:31][CH2:30][CH:29]([N:32]5[CH2:37][CH2:36][N:35]([CH2:38][C:39]([O:41]CC)=[O:40])[CH2:34][CH2:33]5)[CH2:28][CH2:27]4)=[O:25])=[O:21])[CH2:16][CH2:15]3)[CH2:9][CH2:8][C:7]=2[CH:57]=1.[Li+].[OH-]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[NH:12][C:11](=[O:13])[N:10]([CH:14]3[CH2:15][CH2:16][N:17]([C:20]([O:22][C@H:23]([CH2:44][C:45]4[CH:50]=[C:49]([C:51]([F:54])([F:53])[F:52])[C:48]([NH2:55])=[C:47]([Cl:56])[CH:46]=4)[C:24]([N:26]4[CH2:31][CH2:30][CH:29]([N:32]5[CH2:37][CH2:36][N:35]([CH2:38][C:39]([OH:41])=[O:40])[CH2:34][CH2:33]5)[CH2:28][CH2:27]4)=[O:25])=[O:21])[CH2:18][CH2:19]3)[CH2:9][CH2:8][C:7]=2[CH:57]=1