4-Nitrophenyl Acetate → Phenol, 4-amino-, 1-acetate

HRID 22707

Reaction equation

HRID 22707 reaction equation
NC1C=C(OC)C=CC=1O.[C:11]([O:14][C:15]1[CH:20]=[CH:19][C:18]([N+:21]([O-])=O)=[CH:17][CH:16]=1)(=[O:13])[CH3:12].COC1C=CC(O)=C([N+]([O-])=O)C=1.C(OC1C=CC(NC(=O)CCl)=CC=1)(=O)C>>[C:11]([O:14][C:15]1[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][CH:16]=1)(=[O:13])[CH3:12]

Participants

5

Reactant 4

HCID 132434-Nitrophenyl AcetateHCID 15285Phenol, 4-methoxy-2-nitro-HCID 14191082-Amino-4-methoxyphenolHCID 225916104-(2-Chloroacetylamino)phenyl acetate

Product 1

HCID 83783Phenol, 4-amino-, 1-acetate

Procedure

Compound 55 was prepared in the manner of compound 12 substituting 4-nitrophenyl acetate for compound 11 in part C-1 of Example 1. Synthesis of 4-(2-chloroacetylamino)phenyl acetate (56):

Sources & evidence

ORD record
ord-13df66561d6747b989679c3e827236b8
Source dataset
uspto-grants-2005_02
Patent number
US06849632B2

Linked notes

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