Benzoxazole → 6-[(Oxiran-2-yl)methoxy]quinoline
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[CH:5]2.[O:12]1[C:16]2[CH:17]=[CH:18]C=CC=2N=C1>>[O:12]1[CH2:16][CH:17]1[CH2:18][O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[CH:5]2Participants
3
Procedure
Compound 79 was prepared in the manner of compound 6 substituting 6-hydroxyquinoline for compound 8 in part C-5 of Example 1.
Sources & evidence
- ORD record
- ord-44ce2d593c9d45c2af99b4eb343c68d5
- Source dataset
- uspto-grants-2005_02
- Patent number
- US06849632B2
Reaction notes
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