2-Aminothiazole → N-[4-Fluoro-2-(2-fluoro-6-methoxyphenoxy)phenyl]-N'-(thiazol-2-yl)urea

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[C:3]=1[OH:10].F[C:12]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:13]=1[N+:19]([O-:21])=[O:20].[F:22][C:23]1[CH:29]=[CH:28][C:26]([NH2:27])=[C:25]([O:30][C:31]2[C:36]([O:37][CH3:38])=[CH:35][CH:34]=[CH:33][C:32]=2[F:39])[CH:24]=1.[NH2:40][C:41]1[S:42][CH:43]=[CH:44][N:45]=1>>[F:18][C:16]1[CH:17]=[CH:12][C:13]([N+:19]([O-:21])=[O:20])=[C:14]([O:10][C:3]2[C:4]([O:8][CH3:9])=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])[CH:15]=1.[F:22][C:23]1[CH:29]=[CH:28][C:26]([NH:27][C:3]([NH:40][C:41]2[S:42][CH:43]=[CH:44][N:45]=2)=[O:10])=[C:25]([O:30][C:31]2[C:36]([O:37][CH3:38])=[CH:35][CH:34]=[CH:33][C:32]=2[F:39])[CH:24]=1