HCID 66958288, compound → HCID 66959005, compound
Reaction equation
[CH2:1]([C:3]1[N:7]([CH2:8][CH2:9][CH3:10])[N:6]=[C:5]([C:11]([NH2:13])=O)[CH:4]=1)[CH3:2]>P(Cl)(Cl)(Cl)=O>[CH2:1]([C:3]1[N:7]([CH2:8][CH2:9][CH3:10])[N:6]=[C:5]([C:11]#[N:13])[CH:4]=1)[CH3:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
5-Ethyl-1-propyl-1H-pyrazole-3-carboxamide (5.50 g, 30.35 mmol) was treated with phosphorous oxychloride (20 mL) according to the procedure described in Part D of Examples 37-39 to yield 4.89 g of 5-ethyl-1-propyl-1H-pyrazole-3-carbonitrile as an oil.
Sources & evidence
- ORD record
- ord-92b5d0bda313494f8a4cfbc4971e1e2a
- Source dataset
- uspto-grants-2015_09
- Patent number
- US09145410B2
Reaction notes
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