Diisopropylethylamine → 1-[3-(1-{[tert-Butyl(diphenyl)silyl]oxy)-2-methylpropan-2-yl)-1-{3-[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]phenyl}-1H-pyrazol-5-yl]-3-[(1S,4R)-4-({3-[(2S)-2-methylpiperidin-1-yl][1,2,4]triazolo[4,3-a]pyridin-6-yl}oxy)-1,2,3,4-tetrahydronaphthalen-1-yl]urea
Reaction equation
ClC(Cl)(Cl)CO[C:5](=[O:50])[NH:6][C:7]1[N:8]([C:34]2[CH:39]=[CH:38][CH:37]=[C:36]([O:40][CH2:41][CH2:42][O:43][CH:44]3[CH2:49][CH2:48][CH2:47][CH2:46][O:45]3)[CH:35]=2)[N:9]=[C:10]([C:12]([CH3:33])([CH3:32])[CH2:13][O:14][Si:15]([C:28]([CH3:31])([CH3:30])[CH3:29])([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:11]=1.[CH3:53][C@H:54]1[CH2:59][CH2:58][CH2:57][CH2:56][N:55]1[C:60]1[N:64]2[CH:65]=[C:66]([O:69][C@H:70]3[C:79]4[C:74](=[CH:75][CH:76]=[CH:77][CH:78]=4)[C@@H:73]([NH2:80])[CH2:72][CH2:71]3)[CH:67]=[CH:68][C:63]2=[N:62][N:61]=1.CCN(C(C)C)C(C)C>O1CCOCC1>[Si:15]([O:14][CH2:13][C:12]([C:10]1[CH:11]=[C:7]([NH:6][C:5]([NH:80][C@@H:73]2[C:74]3[C:79](=[CH:78][CH:77]=[CH:76][CH:75]=3)[C@H:70]([O:69][C:66]3[CH:67]=[CH:68][C:63]4[N:64]([C:60]([N:55]5[CH2:56][CH2:57][CH2:58][CH2:59][C@@H:54]5[CH3:53])=[N:61][N:62]=4)[CH:65]=3)[CH2:71][CH2:72]2)=[O:50])[N:8]([C:34]2[CH:39]=[CH:38][CH:37]=[C:36]([O:40][CH2:41][CH2:42][O:43][CH:44]3[CH2:49][CH2:48][CH2:47][CH2:46][O:45]3)[CH:35]=2)[N:9]=1)([CH3:33])[CH3:32])([C:28]([CH3:29])([CH3:31])[CH3:30])([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1Participants
5
Reactant 3
HCID 81531Diisopropylethylamine
HCID 86687106(1S,4R)-4-[3-((S)-2-Methyl-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-ylamine
HCID 86687287(5-[2-(tert-Butyl-diphenyl-silanyloxy)-1,1-dimethyl-ethyl]-2-{3-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-2H-pyrazol-3-yl)-carbamic acid 2,2,2-trichloro-ethyl esterProduct 1
