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HRID2288416

Reaction detail

3 reactants → 1 products · 1 solvents Ethanol

EQUATION

Reaction equation

HRID 2288416 reaction equation

Participants

5

Reactant 3

Hydrochloric Acid molecular structure
HCID313

Hydrochloric Acid

ClH

Ammonium Carbonate molecular structure
HCID517111

Ammonium Carbonate

CH2O3.2H3N

Huagongshe compound record HCID 18412482 molecular structure
HCID18412482

Huagongshe compound record HCID 18412482

Product 1

1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide Hydrochloride molecular structure
HCID18412350

1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide Hydrochloride

C27H35ClN6O3

Yield 60%

Reagents, catalysts & solvents 1

Ethanol molecular structure
SolventHCID702

Ethanol

C2H6O

Procedure

Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)-amide and ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 60% of theory, C27H34N6O3 (490.6) EKA mass spectrum: (M+H)+ =491

Sources & evidence

ORD recordord-476fcdb8393f4d1a81356f96dd6001e4
Source datasetuspto-grants-2000_07
DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380

NOTES

Linked notes

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