Tryptamine → Tetrahydro-beta-carboline
Reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1.S(N1CC(C)(C)N(C)C1)([C:16]1C=CC(C)=CC=1)(=O)=O>>[CH2:16]1[C:5]2[NH:6][C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:4]=2[CH2:3][CH2:2][NH:1]1Participants
3
Procedure
treating the 3-(2-amino)ethyl indole with 1-tosyl-3,4,4-trimethylimidazolidine to produce a tetrahydro-β-carboline derivative; and
Sources & evidence
- ORD record
- ord-9dac258e8b0d4c399f0e6a28249b92cf
- Source dataset
- uspto-grants-2000_07
- Patent number
- US06093723
Reaction notes
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