O-methylisourea methyl sulfate → Creatine

HRID 2289873

Reaction equation

[NH:1]([CH2:3][C:4]([O-:6])=[O:5])[CH3:2].[Na+].COS(O)(=O)=O.CO[C:16](=[NH:18])[NH2:17]>>[O:5]=[C:4]([CH2:3][N:1]([C:16](=[NH:17])[NH2:18])[CH3:2])[OH:6]

Participants

Reactant 2

HCID 15405421O-methylisourea methyl sulfate

HCID 23667259Sodium Sarcosinate

Product 1

HCID 586Creatine

Procedure

JP 077364 describes the reaction of a solution of sodium sarcosinate with O-methylisourea methyl sulfate at pH 11 to give creatine.

Sources & evidence

ORD record: ord-5993898377e8417fa538fcf3a0b22d5d
Source dataset: uspto-grants-2000_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06093848

Linked notes

Loading…