Thionyl Chloride → HCID 15098931, compound
Reaction equation
[CH3:1][N:2]1[C:6]([S:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=O)=[N:5][N:4]=[N:3]1.S(Cl)([Cl:16])=O>C1C=CC=CC=1.CN(C=O)C>[CH3:1][N:2]1[C:6]([S:7][CH2:8][CH2:9][CH2:10][C:11]([Cl:16])=[O:13])=[N:5][N:4]=[N:3]1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
2.2 g of 4-(1-methyltetrazol-5-ylthio)-butyric acid are stirred in 20 ml of absolute benzene with 1.03 ml of thionyl chloride and 4 drops of DMF for 20 minutes at the reflux temperature. The solvent is then concentrated by evaporation under reduced pressure. After dissolving and concentrating by evaporation twice more in toluene, the pure title compound is obtained in the form of a yellow oil.
Workup
- concentrationThe solvent is then concentrated by evaporation under reduced pressure
- dissolutionAfter dissolving
- concentrationconcentrating by evaporation twice more in toluene
Sources & evidence
- ORD record
- ord-7ff13846860e4002b9df64feb5c537e8
- Source dataset
- uspto-grants-1986_10
- Patent number
- US04616007
Reaction notes
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