Pyrrolidine → HCID 66738927, compound

HRID 229335

Reaction equation

HRID 229335 reaction equation
[C:1](#[N:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:11][C:12]1[NH:16][N:15]=[C:14]([NH2:17])[CH:13]=1.[NH:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH3:11][C:12]1[NH:16][N:15]=[C:14]([NH:17][C:3]2[CH:2]=[C:1]([N:18]3[CH2:22][CH2:21][CH2:20][CH2:19]3)[N:10]=[C:1]([CH:2]=[CH:3][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=3)[N:10]=2)[CH:13]=1

Participants

4

Reactant 3

HCID 31268PyrrolidineHCID 746673-Phenylprop-2-enenitrileHCID 931461H-Pyrazol-3-amine, 5-methyl-

Product 1

HCID 66738927HCID 66738927, compound

Procedure

Example 76 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and pyrrolidine. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.

Workup

  1. customExample 76 was synthesized via Scheme 6 according to the general scheme
  2. customprovided above with the

Sources & evidence

ORD record
ord-78f024d1d0eb4b008009f325f5671ed3
Source dataset
uspto-grants-2009_07
Patent number
US07563787B2

Linked notes

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