2,3,4,5,6-Pentafluorobenzyl Alcohol → HCID 17989822, compound

HRID 229488

Reaction equation

HRID 229488 reaction equation
[F:1][C:2]1[C:9]([F:10])=[C:8]([F:11])[C:7]([F:12])=[C:6]([F:13])[C:3]=1[CH2:4][OH:5].[ClH:14].[NH2:15][CH2:16][C:17](=[O:23])[CH2:18][CH2:19][C:20](O)=[O:21]>>[ClH:14].[NH2:15][CH2:16][C:17](=[O:23])[CH2:18][CH2:19][C:20]([O:5][CH2:4][C:3]1[C:2]([F:1])=[C:9]([F:10])[C:8]([F:11])=[C:7]([F:12])[C:6]=1[F:13])=[O:21]

Participants

3

Reactant 2

HCID 99232,3,4,5,6-Pentafluorobenzyl AlcoholHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 17989822HCID 17989822, compound

Procedure

From 2,3,4,5,6-pentafluorobenzyl alcohol (5.1 g; 26 mmol) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol). The reaction was complete after 6 days at 100° C. The yield was 0.25 g (13%). Mp 146-148° C.

Sources & evidence

ORD record
ord-a5df7938c9714110acc503e506bc4e72
Source dataset
uspto-grants-2009_07
Patent number
US07563819B1

Linked notes

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