Hydrogen Bromide → Bupropion
Reaction equation
[CH3:1][CH:2]([NH:12][C:13]([CH3:16])([CH3:15])[CH3:14])[C:3]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:11])[CH:10]=1)=[O:4].Cl.Br>>[CH3:1][CH:2]([NH:12][C:13]([CH3:14])([CH3:16])[CH3:15])[C:3]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:11])[CH:10]=1)=[O:4]Participants
3
Reactant 2
Product 1
Procedure
Bupropion HCl was replaced with HBr and adjusted to obtain same amount Bupropion base.
Sources & evidence
- ORD record
- ord-3b0ddbd6c5e14446ae96e7cfcf942fef
- Source dataset
- uspto-grants-2009_07
- Patent number
- US07563823B2
Reaction notes
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