Benzyl Isothiocyanate → 2-[4-benzyl-5-[(pyridine-4-ylmethyl)thio)-4H-1,2,4-triazol-3-yl]pyridine

HRID 229764

Reaction equation

HRID 229764 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([NH:9][NH2:10])=O.[CH2:11]([N:18]=[C:19]=[S:20])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.Br[CH2:22][C:23]1[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=1>>[CH2:11]([N:18]1[C:19]([S:20][CH2:22][C:23]2[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=2)=[N:10][N:9]=[C:7]1[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 2346Benzyl IsothiocyanateHCID 255881PicolinohydrazideHCID 6427994-(Bromomethyl)pyridine

Product 1

HCID 111642502-[4-benzyl-5-[(pyridine-4-ylmethyl)thio)-4H-1,2,4-triazol-3-yl]pyridine

Procedure

This compound was synthesized using the same methodology as described in Example 1 above, using 2-pyridinecarboxylic acid hydrazide, benzyl isothiocyanate and 4-bromomethylpyridine as the starting materials. (M+H)+−360.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-d0bc0f522cc5481daae0550cc372fe0f
Source dataset
uspto-grants-2009_07
Patent number
US07563905B2

Linked notes

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