Oxalyl chloride → 4-Ethyl-4-formylhexanenitrile

HRID 2299054

Reaction equation

HRID 2299054 reaction equation

[CH2:1]([C:3]([CH2:10][CH3:11])([CH2:6][CH2:7][C:8]#[N:9])[CH2:4][OH:5])[CH3:2].C(Cl)(=O)C(Cl)=O>CS(C)=O>[CH2:10]([C:3]([CH:4]=[O:5])([CH2:1][CH3:2])[CH2:6][CH2:7][C:8]#[N:9])[CH3:11]

Participants

4

Reactant 2

HCID 65578Oxalyl chloride

HCID 183797162,2-Diethyl-4-cyanobutanol

Product 1

HCID 762484-Ethyl-4-formylhexanenitrile

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

2,2-Diethyl-4-cyanobutanol, oxalyl chloride and dimethylsulfoxide were processed as described in Example 18A to provide the title compound.

Sources & evidence

ORD record: ord-2718b5aa37c04118a971488eacfe2225
Source dataset: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06495576B2

Linked notes

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