p-Toluenesulfonic acid → N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-diethyl-4-cyanobutyl]-4-chlorobenzamide

HRID 2299055

Reaction equation

HRID 2299055 reaction equation
[CH2:1]([C:3]([CH:10]=O)([CH2:8][CH3:9])[CH2:4][CH2:5][C:6]#[N:7])[CH3:2].[Cl:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([NH2:19])=[O:18])=[CH:15][CH:14]=1.[NH:22]1[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=2[N:24]=[N:23]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:22]1([CH:10]([NH:19][C:17](=[O:18])[C:16]2[CH:20]=[CH:21][C:13]([Cl:12])=[CH:14][CH:15]=2)[C:3]([CH2:1][CH3:2])([CH2:8][CH3:9])[CH2:4][CH2:5][C:6]#[N:7])[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=2[N:24]=[N:23]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 120844-ChlorobenzamideHCID 762484-Ethyl-4-formylhexanenitrileHCID 178418385HCID 178418385, compound

Product 1

HCID 18770751N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-diethyl-4-cyanobutyl]-4-chlorobenzamide

Procedure

The product from Example 19A, 4-chlorobenzamide, benzotriazole, and p-toluenesulfonic acid were processed as described in Example 1C to provide the title compound.

Sources & evidence

ORD record
ord-bf4c2a31513942788a07be5ecd0e2778
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Linked notes

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