Dimethyl methylphosphonate → 1,1-Difluoro-3-amino-3-hydroxymethyl-5-(4-octylphenyl)pentylphosphonic acid
Reaction equation
[NH2:1][C:2]([CH2:21]O)([CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[CH:9][CH:8]=1)[CH2:3][OH:4].[Li].C([Li])CCC.[F:29][CH:30]([P:32](=[O:39])([O:36]CC)[O:33]CC)[F:31].CP(=O)(OC)OC>>[F:29][C:30]([P:32](=[O:33])([OH:39])[OH:36])([F:31])[CH2:21][C:2]([NH2:1])([CH2:3][OH:4])[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[CH:9][CH:8]=1
