Phenylhydrazine → HCID 135487800, compound
Reaction equation
[CH3:1][C:2]1[C:7]([OH:8])=[C:6]2[C:9]([C:11]3[C:30]([C:31](=[O:32])[C:5]2=[CH:4][C:3]=1[OH:36])=[C:29]([OH:33])[C:14]1[C:15]2[C:20]([CH2:21][CH2:22][C:13]=1[C:12]=3[O:34][CH3:35])=[CH:19][C:18]1[CH:23](O)[O:24][C:25](=O)[C:17]=1[C:16]=2[OH:28])=[O:10].[C:37]1([NH:43][NH2:44])[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1>C(O)(=O)C>[C:37]1([N:43]2[C:25](=[O:24])[C:17]3[C:16]([OH:28])=[C:15]4[C:14]5[C:13]([CH2:22][CH2:21][C:20]4=[CH:19][C:18]=3[CH:23]=[N:44]2)=[C:12]([O:34][CH3:35])[C:11]2[C:9](=[O:10])[C:6]3[C:5](=[CH:4][C:3]([OH:36])=[C:2]([CH3:1])[C:7]=3[OH:8])[C:31](=[O:32])[C:30]=2[C:29]=5[OH:33])[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A 5% mixture of madurahydroxylactone in glacial acetic acid is mixed with 2 mole equivalents of phenylhydrazine and boiled under reflux for 30 min. The reaction mixture is then left to stand at room temperature for about 12 hours. The red solid which has crystallized out is filtered off with suction, washed with glacial acetic acid and dried. The crude product is extracted with tetrahydrofuran (THF) in a Soxhlet. On cooling, the product crystallizes out and is filtered off with suction and dried. The yield is about 83% of theory.