Benzyl Bromide → HCID 13938647, compound

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]1[CH:16]=[C:15]([CH3:17])[C:14]([OH:18])=[C:13]([CH3:19])[CH:12]=1)=[C:5]2[CH3:20].[CH2:21](Br)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([O:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]1[CH:16]=[C:15]([CH3:17])[C:14]([OH:18])=[C:13]([CH3:19])[CH:12]=1)=[C:5]2[CH3:20])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 13938646HCID 13938646, compound

Product 1

HCID 13938647HCID 13938647, compound

Procedure

5-Hydroxy-2-(4-hydroxy-3,5-dimethylphenyl)-3-methylindole and benzyl bromide were treated in the same way as in Example 35 to obtain 5-benzyloxy-2-(4-hydroxy-3,5-dimethylphenyl)-3-methylindole.

Sources & evidence

ORD record: ord-553cf8cc900b4e8da4227e790f627a59
Source dataset: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04695581

Reaction notes

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