Potassium Cation → tert-Butyl 4-(2-(2-chloroacetamido)ethyl)-4-hydroxypiperidine-1-carboxylate

Reaction equation

[C:23](=[O:24])([O-:25])[O-:26].[CH3:29][CH2:30][O:31][C:32](=[O:33])[CH3:34].[Cl:1][CH2:2][C:3](=[O:4])[Cl:5].[K+:27].[K+:28].[NH2:6][CH2:7][CH2:8][C:9]1([OH:22])[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1.[OH2:35]>>[Cl:1][CH2:2][C:3](=[O:4])[NH:6][CH2:7][CH2:8][C:9]1([OH:22])[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1

Participants

Reactant 6

HCID 813Potassium Cation2×

HCID 962Water

HCID 6577Chloroacetyl chloride

HCID 8857Ethyl Acetate

HCID 19660Carbonate Ion

HCID 45789931tert-Butyl 4-(2-aminoethyl)-4-hydroxypiperidine-1-carboxylate

Product 1

HCID 57989111

Sources & evidence

ORD record: ord-1aa5fc53abf54d5da3e4561f0db92f67
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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