Dichloromethane → 1-(3,4-Difluorobenzoyl)-3-(RS)-(4-phenylpiperidinylmethyl)-4-(RS)-(3-thienyl)pyrrolidine

HRID 2311035

Reaction equation

HRID 2311035 reaction equation
[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[Cl:42][CH2:43][Cl:44].[F:31][c:32]1[cH:33][c:34]([C:35](=[O:36])[Cl:37])[cH:38][cH:39][c:40]1[F:41].[c:1]1([CH:7]2[CH2:8][CH2:9][N:10]([CH2:13][CH:14]3[CH2:15][NH:16][CH2:17][CH:18]3[c:19]3[cH:20][s:21][cH:22][cH:23]3)[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]2[CH2:8][CH2:9][N:10]([CH2:13][CH:14]3[CH2:15][N:16]([C:35]([c:34]4[cH:33][c:32]([F:31])[c:40]([F:41])[cH:39][cH:38]4)=[O:36])[CH2:17][CH:18]3[c:19]3[cH:20][s:21][cH:22][cH:23]3)[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27245193,4-Difluorobenzoyl chlorideHCID 206944833-(SR)-(4-phenyl piperidinylmethyl)-4-(RS)-(3-thienyl)pyrrolidine

Product 1

HCID 183648201-(3,4-Difluorobenzoyl)-3-(RS)-(4-phenylpiperidinylmethyl)-4-(RS)-(3-thienyl)pyrrolidine

Sources & evidence

ORD record
ord-a9606949c2e34bfa9193dba1677a4e79
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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