Methanol → 3-hydroxy-1-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclobutylacetonitrile
Reaction equation
[CH3:42][OH:43].[NH2:38][CH2:39][CH2:40][NH2:41].[OH:1][CH:2]1[CH2:3][C:4]([n:6]2[n:7][cH:8][c:9](-[c:11]3[c:12]4[c:13]([n:14][cH:15][n:16]3)[n:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:18][cH:19]4)[cH:10]2)([CH2:28][C:29]#[N:30])[CH2:5]1.[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[OH:1][CH:2]1[CH2:3][C:4]([n:6]2[n:7][cH:8][c:9](-[c:11]3[c:12]4[c:13]([n:14][cH:15][n:16]3)[nH:17][cH:18][cH:19]4)[cH:10]2)([CH2:28][C:29]#[N:30])[CH2:5]1Participants
5
