Tetrahydrofuran → 8-(1-Ethyl-propyl)-2,6-dimethyl-3-(2-methyl-thieno[2,3-b]pyridin-3-yl)-imidazo[1,2-b]pyridazine

HRID 2312467

Reaction equation

HRID 2312467 reaction equation
[Br:1][c:2]1[c:3]([CH3:11])[s:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]12.[CH2:12]([CH3:13])[CH:14]([CH2:15][CH3:16])[c:17]1[c:18]2[n:19]([n:20][c:21]([CH3:23])[cH:22]1)[c:24]([I:28])[c:25]([CH3:27])[n:26]2.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Zn:34]>>[c:2]1(-[c:24]2[n:19]3[c:18]([c:17]([CH:14]([CH2:12][CH3:13])[CH2:15][CH3:16])[cH:22][c:21]([CH3:23])[n:20]3)[n:26][c:25]2[CH3:27])[c:3]([CH3:11])[s:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]12

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 23994ZincHCID 577526818-(1-Ethyl-propyl)-3-iodo-2,6-dimethyl-imidazo[1,2-b]pyridazineHCID 688577263-Bromo-2-methylthieno(2,3-b)pyridine

Product 1

HCID 577526418-(1-Ethyl-propyl)-2,6-dimethyl-3-(2-methyl-thieno[2,3-b]pyridin-3-yl)-imidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-ee2ed8d0ba3c4deb854ef2d632065b3d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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