Sodium ion → 3-Bromo-4-[2-(1-pyrrolidinyl)ethoxy]phenyl 6-Methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl Ketone

HRID 2312685

Reaction equation

HRID 2312685 reaction equation
[CH3:11][O:12][c:13]1[cH:14][cH:15][c:16]2[c:17]([s:18][c:19](-[c:31]3[cH:32][cH:33][c:34]([O:37][CH2:38][CH2:39][N:40]4[CH2:41][CH2:42][CH2:43][CH2:44]4)[cH:35][cH:36]3)[c:20]2[C:21](=[O:22])[c:23]2[cH:24][c:25]([Br:30])[c:26]([F:29])[cH:27][cH:28]2)[cH:45]1.[H-:1].[Na+:2].[O:47]=[CH:48][N:49]([CH3:50])[CH3:51].[OH2:46].[OH:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][CH2:9][CH2:10]1>>[O:3]([CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][CH2:9][CH2:10]1)[c:26]1[c:25]([Br:30])[cH:24][c:23]([C:21]([c:20]2[c:16]3[cH:15][cH:14][c:13]([O:12][CH3:11])[cH:45][c:17]3[s:18][c:19]2-[c:31]2[cH:32][cH:33][c:34]([O:37][CH2:38][CH2:39][N:40]3[CH2:41][CH2:42][CH2:43][CH2:44]3)[cH:35][cH:36]2)=[O:22])[cH:28][cH:27]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 762881-PyrrolidineethanolHCID 166653HydrideHCID 211829863-Bromo-4-fluorophenyl 6-methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

Product 1

HCID 211826243-Bromo-4-[2-(1-pyrrolidinyl)ethoxy]phenyl 6-Methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl Ketone

Sources & evidence

ORD record
ord-0dc39b8c90bf4d3da67e25d93b00b38f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

Loading…