Acetonitrile → 5-Iodo-6-methyl-N-[4-(methylsulfonyl)benzyl]-2-oxo-1-[3-(trifluoro-methyl)phenyl]1,2-dihydropyridine-3-carboxamide

HRID 2314910

Reaction equation

HRID 2314910 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([C:19](=[O:20])[NH:21][CH2:22][c:23]2[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[CH3:32])[cH:27][cH:28]2)[c:6](=[O:18])[n:7]1-[c:8]1[cH:9][c:10]([C:14]([F:15])([F:16])[F:17])[cH:11][cH:12][cH:13]1.[CH3:49][C:50]#[N:51].[Cl:52][CH2:53][Cl:54].[I:41][N:42]1[C:43](=[O:44])[CH2:45][CH2:46][C:47]1=[O:48].[OH:33][S:34]([C:35]([F:36])([F:37])[F:38])(=[O:39])=[O:40]>>[CH3:1][c:2]1[c:3]([I:41])[cH:4][c:5]([C:19](=[O:20])[NH:21][CH2:22][c:23]2[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[CH3:32])[cH:27][cH:28]2)[c:6](=[O:18])[n:7]1-[c:8]1[cH:9][c:10]([C:14]([F:15])([F:16])[F:17])[cH:11][cH:12][cH:13]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 6344DichloromethaneHCID 62406Trifluoromethanesulfonic acidHCID 120273N-IodosuccinimideHCID 116196256-methyl-N-[4-(methylsulfonyl)benzyl]-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide

Product 1

HCID 115199335-Iodo-6-methyl-N-[4-(methylsulfonyl)benzyl]-2-oxo-1-[3-(trifluoro-methyl)phenyl]1,2-dihydropyridine-3-carboxamide

Sources & evidence

ORD record
ord-c3d2391d2658455881f2fdd4b019b8a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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