Hydrochloric Acid → D-Valsartan Benzyl Ester

HRID 2315629

Reaction equation

HRID 2315629 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([CH:10]([N:11]([C:12]([CH2:13][CH2:14][CH2:15][CH3:16])=[O:17])[CH2:18][c:19]1[cH:20][cH:21][c:22](-[c:25]2[c:26](-[c:31]3[n:32][n:33][n:34][n:35]3[C:36]([c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)([c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[c:49]3[cH:50][cH:51][cH:52][cH:53][cH:54]3)[cH:27][cH:28][cH:29][cH:30]2)[cH:23][cH:24]1)[CH:55]([CH3:56])[CH3:57])=[O:58].[ClH:59].[O:60]1[CH2:61][CH2:62][O:63][CH2:64][CH2:65]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([CH:10]([N:11]([C:12]([CH2:13][CH2:14][CH2:15][CH3:16])=[O:17])[CH2:18][c:19]1[cH:20][cH:21][c:22](-[c:25]2[c:26](-[c:31]3[nH:32][n:33][n:34][n:35]3)[cH:27][cH:28][cH:29][cH:30]2)[cH:23][cH:24]1)[CH:55]([CH3:56])[CH3:57])=[O:58]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 21840409Benzyl 3-methyl-2-[pentanoyl-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate

Product 1

HCID 178447292D-Valsartan Benzyl Ester

Sources & evidence

ORD record
ord-a43a17fdbfc34b9fbdd3c309a4bb7de8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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