Tricalcium Phosphate → Hydroxylapatite (Ca5(OH)(PO4)3)

HRID 231744

Reaction equation

[P:1]([O-:5])([O-:4])([O-:3])=[O:2].[Ca+2:6].[P:7]([O-:11])([O-:10])([O-:9])=[O:8].[Ca+2].[Ca+2].[OH-].[Ca+2].[OH-]>>[OH-:2].[O-:9][P:7]([O-:11])([O-:10])=[O:8].[O-:3][P:1]([O-:5])([O-:4])=[O:2].[O-:3][P:1]([O-:5])([O-:4])=[O:2].[Ca+2:6].[Ca+2:6].[Ca+2:6].[Ca+2:6].[Ca+2:6]

Participants

Reactant 2

HCID 24456Tricalcium Phosphate

HCID 6093208Calcium Hydroxide

Product 1

HCID 14781Hydroxylapatite (Ca5(OH)(PO4)3)

Procedure

Basically, according to the present invention, an acidic calcium phosphate solution is reacted with a calcium hydroxide solution, with both solutions near saturation when combined, so as to obtain an amorphous hydroxylapatite precipitate without undesired side reactions. After separation and drying, hydroxylapatite precipitate is sintered at 700°-1100°C. for about 5-30 minutes to obtain the desired ceramic hydroxylapatite material.

Sources & evidence

ORD record: ord-26014b10101f447c8a5611614776ac8f
Source dataset: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04849193

Linked notes

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