Chloride → 1-Methyl-3-phenyl-4-[2-hydroxy-2-(4-chlorophenyl)ethyl]piperazine

Reaction equation

[BH4-:24].[CH3:1][N:2]1[CH2:3][CH:4]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[N:5]([CH2:8][C:9](=[O:10])[c:11]2[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]2)[CH2:6][CH2:7]1.[CH3:28][CH2:29][OH:30].[Cl-:27].[Na+:25].[Na+:26]>>[CH3:1][N:2]1[CH2:3][CH:4]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[N:5]([CH2:8][CH:9]([OH:10])[c:11]2[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]2)[CH2:6][CH2:7]1

Participants

Reactant 5

HCID 312Chloride

HCID 702Ethanol

HCID 923Sodium Ion2×

HCID 28123Borohydride

HCID 143023441-Methyl-3-phenyl-4-(4-chlorophenacyl) piperazine

Product 1

HCID 143023451-Methyl-3-phenyl-4-[2-hydroxy-2-(4-chlorophenyl)ethyl]piperazine

Sources & evidence

ORD record: ord-0040fcc9ba4740edb464e741ca2963fc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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