HCID 14555602, compound → HCID 14555603, compound
Reaction equation
[N+:1]([C:4]1[CH:20]=[CH:19][C:7]([O:8][CH:9]([CH3:18])[CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[CH:6][CH:5]=1)([O-])=O>[OH-].[OH-].[Pd+2].C(O)C>[CH3:18][CH:9]([O:8][C:7]1[CH:6]=[CH:5][C:4]([NH2:1])=[CH:20][CH:19]=1)[CH2:10][CH2:11][N:12]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
To 50 mL ethanol is added 28 g (0.1 mol) of 4-[3-(4-nitrophenoxy)butyl]morpholine and 0.5 g of Pd(OH)2. The mixture is hydrogenated at 30 psi. Monitor the reaction by thin-layer chromatography. Upon completion remove the catalyst by suction filtration through celite. Remove the solvent in vacuo to obtain the title compound.