Hydrochloric Acid → HCID 15702746, compound

HRID 232260

Reaction equation

HRID 232260 reaction equation
[C:1]1(=[O:8])[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1.[C-:9]#[N:10].C([Al+]CC)C.Cl>C1(C)C=CC=CC=1>[O:8]=[C:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]([C:9]#[N:10])[CH2:2]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 707232-Cyclohepten-1-oneHCID 16686413Diethyl aluminum cyanide

Product 1

HCID 15702746HCID 15702746, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To 100 mL of toluene add 2-cyclohepten-1-one (11.0 g, 0.1 mol) and 200 mL (1M solution in toluene, 0.2 mol) of diethylaluminum cyanide. Monitor the reaction by thin-layer chromatography. Upon completion add 1M aqueous HCl until gas evolution ceases. Extract twice with 100 mL of ether. Dry the organic phase with Na2SO4. Filter off the drying agent and evaporate the solvent in vacuo to obtain the title compound.

Workup

  1. customMonitor the reaction by thin-layer chromatography
  2. extractionExtract twice with 100 mL of ether
  3. dry with materialDry the organic phase with Na2SO4
  4. filtrationFilter off the drying agent
  5. customevaporate the solvent in vacuo

Sources & evidence

ORD record
ord-e95315393a654245bf2d5423cbf03910
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Linked notes

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