HCID 20031389, compound → HCID 20031360, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-])=O)=[CH:20][CH:19]=3)[CH2:12][CH2:11]2)=[CH:4][CH:3]=1>C(O)(=O)C.Cl.[Pd]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=3)[CH2:14][CH2:15]2)=[CH:6][CH:7]=1Participants
5
Reactant 1
Product 1
Reagents, catalysts & solvents 3
Procedure
In a manner similar to Preparation 3, hydrogenate 1[2-(4-chlorophenyl)ethyl]-4-[(4-nitrophenoxy)methyl]piperidine in acetic acid and hydrochloric acid over palladium on carbon to obtain the title compound.