Phosphorus oxychloride → Ethyl 8-chloro-1-methyl-2-oxo-1,2-dihydropyrido[3,2-d]pyridazine-3-carboxylate

Reaction equation

[CH3:1][n:2]1[c:3](=[O:18])[c:4]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:5][c:6]2[c:7]1[c:8](=[O:12])[nH:9][n:10][cH:11]2.[P:19]([Cl:20])([Cl:21])([Cl:22])=[O:23]>>[CH3:1][n:2]1[c:3](=[O:18])[c:4]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:5][c:6]2[c:7]1[c:8]([Cl:21])[n:9][n:10][cH:11]2

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 66988436Ethyl 1-methyl-2,8-dioxo-1,2,7,8-tetrahydropyrido[2,3-d]pyridazine-3-carboxylate

Product 1

HCID 46930535Ethyl 8-chloro-1-methyl-2-oxo-1,2-dihydropyrido[3,2-d]pyridazine-3-carboxylate

Sources & evidence

ORD record: ord-3f91c61f9cc64529bfe5d7a020768cb8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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