Hydroxide → 2,6-Difluoro-3,5-dimethoxybenzenamine

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[c:10]([F:20])[c:11]([O:18][CH3:19])[cH:12][c:13]([O:16][CH3:17])[c:14]1[F:15].[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[H:21][H:22].[OH-:28].[OH-:30].[Pd+2:29]>>[NH2:8][c:9]1[c:10]([F:20])[c:11]([O:18][CH3:19])[cH:12][c:13]([O:16][CH3:17])[c:14]1[F:15]

Participants

Reactant 5

HCID 961Hydroxide2×

HCID 8028Tetrahydrofuran

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 18444842N-benzyl-2,6-difluoro-3,5-dimethoxyaniline

HCID 178418361HCID 178418361, compound

Product 1

HCID 102618922,6-Difluoro-3,5-dimethoxybenzenamine

Sources & evidence

ORD record: ord-4f2d0d93dad94a04a254763d382988e4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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