Dimethylformamide → HCID 19964804, compound

HRID 233008

Reaction equation

HRID 233008 reaction equation
[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:25]=[C:26]([C:30]3[N:31]=[C:32]4[CH2:37][CH2:36][CH2:35][CH2:34][N:33]4[CH:38]=3)[CH:27]=[C:28]([CH3:29])[C:6]=2[N:5]=1)[CH2:2][CH3:3].ClC[CH2:41][C:42]([CH3:47])([CH3:46])[C:43]([O-:45])=[O:44].[CH3:48]N(C)C=O>>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]([O:24][CH2:48][O:45][C:43](=[O:44])[C:42]([CH3:47])([CH3:46])[CH3:41])=[O:23])=[CH:12][CH:11]=2)[C:7]2[CH:25]=[C:26]([C:30]3[N:31]=[C:32]4[CH2:37][CH2:36][CH2:35][CH2:34][N:33]4[CH:38]=3)[CH:27]=[C:28]([CH3:29])[C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 19964521HCID 19964521, compoundHCID 217530474-Chloro-2,2-dimethylbutanoate

Product 1

HCID 19964804HCID 19964804, compound

Procedure

Prepared analogously to Example 215 from 4'-[(2-n-propyl-4-methyl-6-(5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid and chloromethylpivalate in dimethylformamide.

Sources & evidence

ORD record
ord-ec364cfab8e742bca3577e3a62063aee
Source dataset
uspto-grants-1997_01
Patent number
US05591762

Linked notes

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