Dimethylformamide → [4-(4-[1,2,3]Triazol-1-yl-butyl)-phenyl]-[2-(5-trifluoromethoxy-1H-indol-2-yl)-oxazol-4-ylmethyl]-carbamic acid tert-butyl ester

HRID 2330431

Reaction equation

HRID 2330431 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][cH:10][c:11]([CH2:14][CH2:15][CH2:16][CH2:17][n:18]2[n:19][n:20][cH:21][cH:22]2)[cH:12][cH:13]1)=[O:23].[CH:45]([N:46]([CH3:47])[CH3:48])=[O:49].[Cl:24][CH2:25][c:26]1[n:27][c:28](-[c:31]2[nH:32][c:33]3[cH:34][cH:35][c:36]([O:40][C:41]([F:42])([F:43])[F:44])[cH:37][c:38]3[cH:39]2)[o:29][cH:30]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([c:8]1[cH:9][cH:10][c:11]([CH2:14][CH2:15][CH2:16][CH2:17][n:18]2[n:19][n:20][cH:21][cH:22]2)[cH:12][cH:13]1)[CH2:25][c:26]1[n:27][c:28](-[c:31]2[nH:32][c:33]3[cH:34][cH:35][c:36]([O:40][C:41]([F:42])([F:43])[F:44])[cH:37][c:38]3[cH:39]2)[o:29][cH:30]1)=[O:23]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 69220256[4-(4-[1,2,3]Triazol-1-yl-butyl)phenyl]-carbamic acid tert-butyl esterHCID 1363319652-(4-chloromethyl-oxazol-2-yl)-5-trifluoromethoxy-1H-indole

Product 1

HCID 136331972[4-(4-[1,2,3]Triazol-1-yl-butyl)-phenyl]-[2-(5-trifluoromethoxy-1H-indol-2-yl)-oxazol-4-ylmethyl]-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-bde672f67841481f9204a61942e69cb0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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