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Carbon Dioxide → 2-(4-Chloro-phenyl)-4-(2-hydroxy-ethyl)-thiazole-5-carboxylic acid

HRID 2335758
Notes
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Reaction equation

HRID 2335758 reaction equation
[C:21](=[O:22])=[O:23].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:16][CH2:17][CH2:18][CH2:19][Li:20].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[s:9][cH:10][c:11]([CH2:13][CH2:14][OH:15])[n:12]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[s:9][c:10]([C:21](=[O:22])[OH:23])[c:11]([CH2:13][CH2:14][OH:15])[n:12]2)[cH:6][cH:7]1
ParticipantsSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 280Carbon DioxideHCID 8028TetrahydrofuranHCID 6105314-Thiazoleethanol, 2-(4-chlorophenyl)-HCID 178418339Butyllithium

Product 1

HCID 575016942-(4-Chloro-phenyl)-4-(2-hydroxy-ethyl)-thiazole-5-carboxylic acid

Sources & evidence

ORD record
ord-47745bc20d464e0bba0f9d5865d5ed80
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes