Methanol → 3'-Fluoro-4'-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-3-methylbiphenyl-4-carboxylic acid

HRID 2335950

Reaction equation

HRID 2335950 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:30][OH:31].[F:1][c:2]1[cH:3][c:4](-[c:19]2[cH:20][c:21]([CH3:29])[c:22]([C:25](=[O:26])[O:27][CH3:28])[cH:23][cH:24]2)[cH:5][cH:6][c:7]1[NH:8][c:9]1[s:10][c:11]2[c:12]([n:13]1)[cH:14][cH:15][c:16]([F:18])[cH:17]2.[Na+:34].[OH-:33].[OH2:32]>>[F:1][c:2]1[cH:3][c:4](-[c:19]2[cH:20][c:21]([CH3:29])[c:22]([C:25](=[O:26])[OH:27])[cH:23][cH:24]2)[cH:5][cH:6][c:7]1[NH:8][c:9]1[s:10][c:11]2[c:12]([n:13]1)[cH:14][cH:15][c:16]([F:18])[cH:17]2

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 59385264Methyl 3'-fluoro-4'-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-3-methylbiphenyl-4-carboxylate

Product 1

HCID 593852543'-Fluoro-4'-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-3-methylbiphenyl-4-carboxylic acid

Sources & evidence

ORD record
ord-2e97dccc41c34b93a59d05cb31e53e50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

Loading…