Tetrahydrofuran → 4,4-dimethyl-7-(1-pentyl-prop-2-ynyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH3:28])([CH3:29])[c:12]2[cH:13][cH:14][c:15]([CH:18]([CH:19]=[C:20]([Br:21])[Br:22])[CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[cH:16][c:17]21.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Li:30][CH2:31][CH2:32][CH2:33][CH3:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH3:28])([CH3:29])[c:12]2[cH:13][cH:14][c:15]([CH:18]([C:19]#[CH:20])[CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[cH:16][c:17]21