Dimethylformamide → Ethyl 5-[2-(5-methyl-2-phenyl-1,3-thiazol-4-yl)ethoxy]-1-(tetrahydro-2-furanylmethyl)-1H-indole-2-carboxylate

HRID 2336797

Reaction equation

HRID 2336797 reaction equation
[Br:36][CH2:37][CH:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[C:30](=[O:31])([O-:32])[O-:33].[CH3:1][c:2]1[c:3]([CH2:13][CH2:14][O:15][c:16]2[cH:17][c:18]3[cH:19][c:20]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[nH:21][c:22]3[cH:23][cH:24]2)[n:4][c:5](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[s:6]1.[CH3:43][N:44]([CH3:45])[CH:46]=[O:47].[Cs+:34].[Cs+:35]>>[CH3:1][c:2]1[c:3]([CH2:13][CH2:14][O:15][c:16]2[cH:17][c:18]3[cH:19][c:20]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[n:21]([CH2:37][CH:38]4[O:39][CH2:40][CH2:41][CH2:42]4)[c:22]3[cH:23][cH:24]2)[n:4][c:5](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[s:6]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 14501Furan, 2-(bromomethyl)tetrahydro-HCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 22676745ethyl 5-[2-(5-methyl-2-phenyl-1,3-thiazol-4-yl)ethoxy]-1H-indole-2-carboxylate

Product 1

HCID 22676841Ethyl 5-[2-(5-methyl-2-phenyl-1,3-thiazol-4-yl)ethoxy]-1-(tetrahydro-2-furanylmethyl)-1H-indole-2-carboxylate

Sources & evidence

ORD record
ord-9a20d48e3dde48b4944eb8594c44d638
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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