Dimethylformamide → 7-Benzyloxy-4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxycinnoline

HRID 2338013

Reaction equation

HRID 2338013 reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:20][CH3:21])[cH:11][c:12]2[c:13]([Cl:19])[cH:14][n:15][n:16][c:17]2[cH:18]1.[Cs+:38].[Cs+:39].[F:22][c:23]1[c:24]2[cH:25][c:26]([CH3:33])[nH:27][c:28]2[cH:29][cH:30][c:31]1[OH:32].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:20][CH3:21])[cH:11][c:12]2[c:13]([O:32][c:31]3[c:23]([F:22])[c:24]4[cH:25][c:26]([CH3:33])[nH:27][c:28]4[cH:29][cH:30]3)[cH:14][n:15][n:16][c:17]2[cH:18]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 103520364-fluoro-2-methyl-1H-indol-5-olHCID 219910087-Benzyloxy-4-chloro-6-methoxy cinnoline

Product 1

HCID 101374817-Benzyloxy-4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxycinnoline

Sources & evidence

ORD record
ord-5be53dcbcb554f4ba67eb6f8d2879677
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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