Hydrochloric Acid → HCID 57111376, compound
Reaction equation
[F:1][CH:2]([O:7][C:8]1[CH:14]=[CH:13][C:11]([NH2:12])=[CH:10][CH:9]=1)[C:3]([F:6])([F:5])[F:4].Cl.[O-:16][C:17]#[N:18].[K+]>O>[F:1][CH:2]([O:7][C:8]1[CH:14]=[CH:13][C:11]([NH:12][C:17]([NH2:18])=[O:16])=[CH:10][CH:9]=1)[C:3]([F:4])([F:5])[F:6]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
10 g of 4-tetrafluoroethoxyaniline, prepared as in Example 1, in 40 ml of water, and 10 ml of 1:1 HCl, were reacted with 3.9 g of potassium cyanate. The mixture was stirred for 30 minutes and the formed solid was filtered out, rinsed with cool water, and dried to give 10.5 g of the desired compound, having a melting point of 167°-168° C.
Workup
- filtrationthe formed solid was filtered out
- washrinsed with cool water
- customdried
Sources & evidence
- ORD record
- ord-cc37b8eed65d4e128faac90e168f2d02
- Source dataset
- uspto-grants-1989_10
- Patent number
- US04874786
Reaction notes
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