Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine
Reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.C(O)(=O)C#CCCCCC.[CH:36]1([N:42]=[C:43]=[N:44][CH:45]2[CH2:50][CH2:49][CH2:48]CC2)CCCCC1>O1CCCC1>[CH3:1][N:42]([C:43]1[CH:48]=[CH:49][CH:50]=[CH:45][N:44]=1)[CH3:36]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Following a procedure similar to that described in Example 12, but using 730 mg of radicicol, 701 mg of 2-octynoic acid, 15 ml of dry tetrahydrofuran, 1.03 g of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 611 mg of the title compound were obtained.
Sources & evidence
- ORD record
- ord-e8cb5683bfa0453284eacdc2472eb575
- Source dataset
- uspto-grants-1997_01
- Patent number
- US05597846
Reaction notes
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